LINKS TO HLRCC RESEARCH - Fibroids (Uterine Leiomyoma and Leiomyosarcoma)
The articles referenced in the general section also contain information about uterine leiomyoma (fibroids), whereas the following articles are specific.
These links contains a lot of information about fibroid symptoms and treatments. However some are not HLRCC specific and some treatments may be not recommended for HLRCC. Consult the HLRCC Handbook for its recommendations.Uterine Fibroids Health Center
Description of uterine fibroids and treatment options.Uterine Fibroids(Benign Tumors Of The Uterus)
Description of uterine fibroids and treatment options.Uterine Fibroids Treatment that is Not Invasive
Gives information about using ultrasound to destroy fibroids.Differentiating uterine leiomyomas (fibroids) from uterine sarcomas
Up-to-date information for people worried about possible leiomyosarcoma.
2013Comparison of the effects of gonadotropin-releasing hormone and raloxifeneon the size of uterine leiomyoma
This study showed that raloxifene is an appropriate medicine to reduce the size of uterine leiomyoma and is more effective than GnRH.
2011Magnetic Resonance–guided Focused Ultrasound of Uterine Leiomyomas: Review of a 12-month Outcome of 130 Clinical Patients
This is a link to the abstract; the full article is available on subscription. Follow up of 120 patients from 2005 showing no increase of problems over other more invasive treatments.Big Concerns about Inadvertent Use of Morcellation in Previously Undiagnosed Uterine Leiomyosarcoma
Morcellation is not recommended for HLRCC and this paper adds to that recommendation.
2008Association of Germline Mutations in the Fumarate Hydratase Gene and Uterine Fibroids in Women With Hereditary Leiomyomatosis and Renal Cell Cancer
Paper on analysis of study of fibroids for HLRCC females.MOLECULAR AND CLINICAL CHARACTERISTICS OF TRICARBOXYLIC ACID CYCLE-ASSOCIATED TUMORS
A comprehensive document which importantly reclassifies previous HLRCC uterine leiomyosarcoma under a new classification protocol to atypical uterine leiomyoma.
2007Uterine Fibroids Linked to Renal Cell Cancer in Small Group of Patients
This article relates to fibroids generally and describes the possible HLRCC connection.Genetic heterogeneity among uterine leiomyomata: insights into malignant progression
The malignant transformation of a uterine leiomyoma to a uterine leiomyosarcoma is rare, 1:200,000 is in the literature, but is a source of worry. This article gives a good description of the subject.
2002Edited excerpts from our book A Gynecologist's Second Opinion
Gives descriptions of alternatives to having complete hysterectomies. Please remember to consult the HLRCC Handbook for its recommendations.