LINKS TO HLRCC RESEARCH - Fibroids (Uterine Leiomyoma and Leiomyosarcoma)

The articles referenced in the general section also contain information about uterine leiomyoma (fibroids), whereas the following articles are specific.

These links contains a lot of information about fibroid symptoms and treatments. However some are not HLRCC specific and some treatments may be not recommended for HLRCC. Consult the HLRCC Handbook for its recommendations.

Uterine Fibroids Health Center

Description of uterine fibroids and treatment options.

Uterine Fibroids(Benign Tumors Of The Uterus) Melissa Conrad Stöppler, William C. Shiel Jr.

Description of uterine fibroids and treatment options.

Uterine Fibroids Treatment that is Not Invasive

Gives information about using ultrasound to destroy fibroids.

Differentiating uterine leiomyomas (fibroids) from uterine sarcomas

Up-to-date information for people worried about possible leiomyosarcoma.

2013

Comparison of the effects of gonadotropin-releasing hormone and raloxifeneon the size of uterine leiomyoma Farnaz Zandvakili, Fariba Seyedoshohadaie, Masoumeh Rezaiee, Nasrin Soofizade, Fariba Farhadifar and Ebrahim Ghaderi ,2013

This study showed that raloxifene is an appropriate medicine to reduce the size of uterine leiomyoma and is more effective than GnRH.

2011

Magnetic Resonance–guided Focused Ultrasound of Uterine Leiomyomas: Review of a 12-month Outcome of 130 Clinical Patients Krzysztof R. Gorny, David A. Woodrum, Douglas L. Brown, Tara L. Henrichsen, Amy L. Weaver, Kimberly K. Amrami, Nicholas J. Hangiandreou, Heidi A. Edmonson, Esther V. Bouwsma, Elizabeth A. Stewart, Bobbie S. Gostout, Dylan A. Ehman, and Gina K. Hesley ,2011

This is a link to the abstract; the full article is available on subscription. Follow up of 120 patients from 2005 showing no increase of problems over other more invasive treatments.

Big Concerns about Inadvertent Use of Morcellation in Previously Undiagnosed Uterine Leiomyosarcoma Oncology Times, 2011

Morcellation is not recommended for HLRCC and this paper adds to that recommendation.

2008

Association of Germline Mutations in the Fumarate Hydratase Gene and Uterine Fibroids in Women With Hereditary Leiomyomatosis and Renal Cell Cancer Laveta Stewart, Gladys M. Glenn, Pamela Stratton; Alisa M. Goldstein,Maria J. Merino; Margaret A. Tucker, W. Marston Linehan and Jorge R. Toro, 2008

Paper on analysis of study of fibroids for HLRCC females.

MOLECULAR AND CLINICAL CHARACTERISTICS OF TRICARBOXYLIC ACID CYCLE-ASSOCIATED TUMORS Heli Lehtonen, 2008

A comprehensive document which importantly reclassifies previous HLRCC uterine leiomyosarcoma under a new classification protocol to atypical uterine leiomyoma.

2007

Uterine Fibroids Linked to Renal Cell Cancer in Small Group of Patients Jean Johnson for Fibroids1 2007

This article relates to fibroids generally and describes the possible HLRCC connection.

Genetic heterogeneity among uterine leiomyomata: insights into malignant progression Jennelle C. Hodge and Cynthia C. Morton 2007

The malignant transformation of a uterine leiomyoma to a uterine leiomyosarcoma is rare, 1:200,000 is in the literature, but is a source of worry. This article gives a good description of the subject.

2002

Edited excerpts from our book A Gynecologist's Second Opinion William H. Parker

Gives descriptions of alternatives to having complete hysterectomies. Please remember to consult the HLRCC Handbook for its recommendations.

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Last modified: April 26 2016 19:30:18.