LINKS TO HLRCC RESEARCH - General

Powerpoint presentation of HLRCC Valerie Tokarz

A quick overview as slides.

2014

Hereditary leiomyomatosis and renal cell carcinoma Laura S Schmidt and W Marston Linehan, 2014

A complete description of HLRCC as a downloadable PDF.

Genetics of Kidney Cancer (Renal Cell Cancer) (PDQ®)) USA National Cancer Institute (NCI/NIH) 2014

A definitive medical perspective of HLRCC and FD

Hereditary Kidney Cancer Syndromes(Hereditary Leiomyomatosis and Kidney Cell Cancer (Type 2 Papillary)) Naomi B. Haas, Katherine L. Nathanson, 2014

Good overview of HLRCC.

2011

Hereditary Leiomyomatosis and Renal Cell CancerUpdated Jan, 2011 Oncologist-approved cancer information from the American Society of Clinical Oncology

Overview of HLRCC with a number of useful links to other resources.

Hereditary leiomyomatosis and renal cell cancer: update on clinical and molecular characteristics Heli J. Lehtonen, 2011

The link is to the article abstract. The full article PDF is available on subscription. This document describes fully the current known status of HLRCC, surveillance and treatments.

Hereditary leiomyomatosis and renal cell cancer presenting as metastatic kidney cancer at 18 years of age: implications for surveillance Karin Y. van Spaendonck-Zwarts, Sadhanna Badeloe, Sjoukje F. Oosting, Sjoerd Hovenga, Harry J. F. Semmelink, R. Jeroen A. van Moorselaar, Jan Hein van Waesberghe, Arjen R. Mensenkamp and Fred H. Menko, 2011

This is an important HLRCC article for giving screening recommendations and current treatments for metastatic RCC.

2010

Hereditary Leiomyomatosis and Renal Cell Cancer HLRCC Pithukpakorn and Toro 2006 Updated 2010

Comprehensive description of HLRCC with many references.

A case report of hereditary leiomyomatosis and renal cell cancer K. Frey, MD, Michael J. Worley Jr, MD, Katherine P. Heyman, BA, Thomas A. Caputo, MD 2010

This is a short case study showing that HLRCC knowledge has been developing over the last few years. It has 2 useful figures and a good description.

Hereditary leiomyomatosis and renal cell cancer in families referred for fumarate hydratase germline mutation analysis DL Smit, AR Mensenkamp, S Badeloe, MH Breuning,MEH Simon, KY van,Spaendonck, CMAalfs, JG Post, S Shanley, IPC Krapels, LH Hoefsloot, RJA van Moorselaar, TM Starink, J-P Bayley, J Frank, MAM van Steenseland, FH Menko, 2010

The link is to the article abstract. The full article PDF is available on reduced subscription for patients/caregivers. Comprehensive technical description of HLRCC in 33 families in the Netherlands.

2009

Clinical and molecular genetic aspects of hereditary multiple cutaneous leiomyomatosis Sadhanna Badeloe, Jorge Frank, 2009

Comprehensive technical description of HLRCC with a lot of genetic information and 99 references and 3 cutaneous leiomyomas photos. There is a list of possible treatments for painful leiomyomas.

2008

HLRCC - Genetics Home Reference

Comprehensive description of HLRCC dated 2008 with many links into NIH information.

2007

Hereditary leiomyomatosis and renal cell cancer: a syndrome associated with an aggressive form of inherited renal cancer Robert L. Grubb, III, Michael E. Franks, Jorge Toro, Lindsay Middelton, Lynda Choyke, Sarah Fowler, Carlos Torres-Cabala, Gladys M. Glenn, Peter Choyke,Maria J. Merino, Berton Zbar, Peter A. Pinto, Ramaprasad Srinivasan, Jonathan A. Colemanand, and W. Marston Linehan, 2007

The link is to the article abstract. The full article PDF is available on subscription. This document describes the aggressive nature of RCC in HLRCC.

Mechanisms of Disease: Hereditary Leiomyomatosis Renal Cell Cancer -- A Distinct Form of Hereditary Kidney Cancer Sunil Sudarshan, Peter A Pinto, Len Neckers, and W Marston Linehan,2007

Comprehensive description of HLRCC with many references.

Alternative Link

2006

Cutaneous Leiomyomas: Clinical Marker for Hereditary Leiomyomatosis and Renal Cell Cancer: Cutaneous Leiomyomas: Symptoms, Distribution, Appearance, and Pathology Laveta Stewart; Gladys Glenn; Jorge R. Toro, 2006

Comprehensive description of HLRCC over 10 sections with many references and leiomyoma photographs and descriptions of pain relief treatments

THE ROLE OF FUMARASE (FH) IN TUMORIGENESISLehtonen.2006

This is a large, highly technical documents of academic dissertations from Department of Medical Genetics Molecular and Cancer Biology Program Haartman Institute and Biomedicum Helsinki University of Helsinki Finland. It is a foundation medical document of HLRCC and is included for reference purposes. Of interest to anyone wishing to have a historically complete understanding of the condition.

2005

Clinical Features of Multiple Cutaneous and Uterine Leiomyomatosis N. Afrina Alam, Ella Barclay, Andrew J. Rowan, Jonathan P. Tyrer, Eduardo Calonje, Sanjiv Manek, David Kelsell, Irene Leigh, Simon Olpin and Ian P. M. Tomlinson,2005

A paper describing the results of a study of leiomyomatosis on many individuals. The dilemma of screening recommendations is well described.

2003

Mutations in the Fumarate Hydratase Gene Cause Hereditary Leiomyomatosis and Renal Cell Cancer in Families in North America" Jorge R. Toro, Michael L. Nickerson, Ming-Hui Wei, Michelle B. Warren, Gladys M. Glenn, Maria L. Turner, Laveta Stewart, Paul Duray, Ousman Tourre, Nirmala Sharma, Peter Choyke, Pamela Stratton, Maria Merino, McClellan M. Walther, W. Marston Linehan, Laura S. Schmidt, and Berton Zbar, 2003

This is one of the original pioneering papers on HLRCC.

2002

MOLECULAR BASIS OF HEREDITARY LEIOMYOMATOSIS AND RENAL CELL CANCER (HLRCC) Maija Kiuru, 2002

This is a large, highly technical documents of academic dissertations from Department of Medical Genetics Molecular and Cancer Biology Program Haartman Institute and Biomedicum Helsinki University of Helsinki Finland. It is a foundation medical document of HLRCC and is included for reference purposes. Of interest to anyone wishing to have a historically complete understanding of the condition.

2001

Familial Cutaneous Leiomyomatosis Is a Two-Hit Condition Associated with Renal Cell Cancer of Characteristic Histopathology Maija Kiuru, Virpi Launonen, Marja Hietala, Kristiina Aittomäki, Outi Vierimaa, Reijo Salovaara, Johanna Arola, Eero Pukkala, Pertti Sistonen, Riitta Herva, and Lauri A. Aaltonen,2001

Inherited susceptibility to uterine leiomyomas and renal cell cancer Virpi Launonen, Outi Vierimaa, Maija Kiuru, Jorma Isola, Stina Roth, Eero Pukkala, Pertti Sistonen, Riitta Herva, and Lauri A. Aaltonen, 2001

These are the first papers describing the relationship of cutaneous and uterine leiomyoma with RCC as HLRCC.

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Last modified: April 26 2016 19:30:19.